Lou, 2000 (diode laser clinical data)

Lou, 2000

Title: Prospective study of hair reduction by diode laser (800 nm) with long-term follow-up.

Authors: Lou WW, Quintana AT, Geronemus RG, Grossman MC

Journal: Dermatol Surg 2000 May;26(5):428-32


Affiliated institution: Laser and Skin Surgery Center of New York, New York, USA.

BACKGROUND: Multiple laser systems are available for the purpose of hair removal.

OBJECTIVE: The purpose of this study was to determine the safety and long-term efficacy of the 800 nm, pulsed diode laser at reducing hair count.

METHODS: Fifty volunteers, primarily Fitzpatrick skin types II and III, with dark brown or black hair, were treated with a diode laser (800 nm, 10-40 J/cm2, 5-30 msec, 9 mm 9 mm, 5 degrees C chilled handpiece). Each subject had eight treatment sites at varying fluences and pulse durations, as well as a varying number of treatments and pulses. Hair counts were obtained at each site at baseline, 1, 3, 6, 9, and an average of 20 months after treatment.

RESULTS: After one treatment, hair regrowths ranged from 22 to 31% at the 1-month follow-up visit, then remained stable between 65 and 75% from the 3-month to the averaged 20-month follow-up. After two treatments there were relatively longer growth delays, with hair regrowths plateauing beginning at 6 months after treatment and ranging from 47 to 66% for the remainder of the follow-up evaluations. Side effects were limited to pigmentary changes, transient in subjects with skin types II and III.

CONCLUSIONS: This 800 nm diode laser with a chilled sapphire tip and variable pulse duration is safe and effective for long-term hair reduction in individuals with skin types II and III.

Earlier citation by these authors: Grossman (1998):