Harley, 1976 Title: Follow-up study of patients treated
by x-ray epilation for tinea capitis. Estimation of the dose to
the thyroid and pituitary glands and other structures of the head
and neck.
Authors: Harley NH, Albert RE, Shore RE, Pasternack
BS
Journal: Phys Med Biol 1976 Jul;21(4):631-42
PMID: 972927, UI: 77013736
This study is a further investigation of radiation dose to various
head structures in the children given X-ray therapy for tinea
capitis (ringworm of the scalp). In this work, estimates of the
dose to the thyroid and pituitary gland were obtained with lithium
fluoride thermoluminescent dosemeters using a child's head phantom.
Doses were also measured for the parotid gland and several skin
sites where skin tumours developed in the irradiated cases. In
a previous study, brain and scalp doses of 140 and 500-800 rad
had been estimated for the treated group using this same head
phantom. In this work dosemeters were also placed in the same
brain locations so that comparisons could be obtained between
the two studies. The thyroid dose was estimated to be 6 +/- 2
rad and the pituitary dose was 49 +/- 6 rad for the conventional
tinea capitis treatment. The dose to the parotid gland was 39
rad and the dose to skin sites on the face and neck where tumours
occurred ranged from 20 to 40 rad. The data for the thyroid adenoma
response from this and other studies involving irradiation of
children suggests a linear dose-response relationship within the
first 30-40 years after exposure with a risk of about 0-04% per
rad.
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