Wagner, 1994  Title: A double-blind placebo controlled study
of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia
during thermolysis.
Author: Wagner RF Jr, Flores CA, Argo LF
Journal: Dermatol Surg Oncol 1994 Feb;20(2):148-50
PMID: 18113509, UI: 94157208
Affiliated institution: University
of Texas Medical Branch Thermolysis Clinic, Department of Dermatology,
Galveston 77555-0783.
Cited in:
BACKGROUND. Electrolysis and thermolysis are commonly used electrosurgical
methods for the permanent destruction of unwanted hair. However,
patient fear of pain during treatment may interfere with or even
prevent desired treatment of hirsutism on sensitive areas such
as the upper lip.
OBJECTIVE. This study was conducted to assess the efficacy of
EMLA (Eutetic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine
cream, as a topically applied local anesthetic during thermolysis
on the upper lip.
METHODS. A double-blind placebo control study was conducted by
the University of Texas Medical Branch thermolysis clinic. Thirty
women with idiopathic hirsutism of the upper lip were studied.
Pain was measured with a 100 mm visual analog scale (VAS).
RESULTS. Total paired VAS score differences comparing the placebo
VAS scores to the EMLA VAS scores were significant by paired t-test
(P = .0001). Adverse reactions were mild and transient.
CONCLUSION. EMLA cream may have multiple applications to the
practice of dermatologic surgery, including topically achieved
local anesthesia during thermolysis and electrolysis.
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