Lycka, 1992  Title: EMLA. A new and effective topical anesthetic.
Author: Lycka BA
Journal: J Dermatol Surg Oncol 1992 Oct;18(10):859-62
Comment in: J Dermatol Surg Oncol 1994 Mar;20(3):223
PMID: 1430539, UI: 93055837
Affiliated institution: University
of Alberta, Edmonton, Canada.
Cited in:
A eutectic mixture of local anesthetics (EMLA) contains 2.5%
lidocaine and 2.5% prilocaine in an oil and water emulsion and
has been found to give effective, safe analgesia on normal and
diseased skin, making it useful for numerous medical and surgical
procedures, such as anesthesia for superficial surgery, split-thickness
skin grafts, venipuncture, argon laser treatment, epilation, and
debridement of infected ulcers. Other indications have included
use in postherpetic neuralgia, hyperhidrosis, painful ulcers,
and inhibition of itching and burning. To be effective, EMLA should
ideally be applied to the desired area for at least 1 hour under
an occlusive dressing. The medication has been approved since
May 1991 in Canada for use on intact skin and has been available
in Europe for many years. This study discusses the background,
efficacy, and current and potential uses of EMLA.
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