Choy, 1999  Title: Comparison of lignocaine-prilocaine
cream and amethocaine gel for local analgesia before venepuncture
in children.
Author: Choy L, Collier J, Watson AR
Journal: Acta Paediatr 1999 Sep;88(9):961-4
PMID: 10519337, UI: 99446826
Affiliated institution: Faculty of
Medicine and Health Sciences, University of Nottingham, UK.
Cited in:
The efficacy of lignocaine-prilocaine cream (EMLA) and amethocaine
gel (Ametop) in reducing the pain and distress of venepuncture
was compared in a single-blind randomized study of 34 children
aged 1-14 y. The influences of age, anxiety and past experience
were also investigated. Pain was assessed by the researcher using
the Observation Scale of Behavioural Distress, and by the parent,
doctor and child (if old enough) using a 10-cm, 100-point Visual
Analogue Scale (VAS). Doctors also completed a simple rating scale
for difficulty of venepuncture. Compared to older children, infants
had significantly more anxious parents and were more distressed
when being held still. Anticipatory anxiety correlated with higher
pain ratings. No differences in the analgesic effect of the two
preparations were found. We conclude that whilst EMLA and Ametop
are equally effective at reducing the pain of needle puncture,
under some circumstances the use of Ametop may be more advantageous.
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