Kvedar, 1985  Title: Hirsutism: evaluation and treatment.
Authors: Kvedar JC, Gibson M, Krusinski PA
Journal: J Am Acad Dermatol 1985 Feb;12(2 Pt
1):215-25
PMID: 3156157, UI: 85131980
Affiliated institution:
Cited in: Lin, Dierickx
Hirsutism, a troublesome cosmetic problem, may also
be a sign of serious systemic disease that can be screened for
by means of the patient's history, physical examination, and certain
basic blood tests. Most patients with functional hirsutism have
elevated production rates of testosterone, elevated metabolic
clearance rates of testosterone, depressed levels of sex hormone-binding
globulin, and elevated levels of serum-free testosterone and hair
follicle sensitivity. Once a neoplastic source is ruled out and
hirsutism established as functional, essentially empiric treatment,
including low-dose dexamethasone, oral contraceptives, and spironolactone,
has proved to be effective.
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