Kim, 1995  Title: Regrowth of grafted human scalp hair
after removal of the bulb.
Authors: Kim JC, Choi YC
Journal: Dermatol Surg 1995 Apr;21(4):312-3
PMID: 7728481, UI: 95245709
Affiliated institution: Department
of Immunology, School of Medicine, Kyung-pook National University,
Taegu, Seoul, Korea.
Cited in: Solomon
BACKGROUND. The bulbar region of the hair follicle
contains the dermal papilla, hair germinative epithelial component,
and active melanocytes. Thus, it has been assumed that the bulbar
region plays a central role in hair growth, differentiation, and
pigmentation. OBJECTIVE. To assess the regenerative capacity of
human hair.
METHODS. Individual anagen hair follicles were isolated
from the occipital scalp and grafted onto the leg after removal
of the bulb.
RESULTS. The grafts of follicles from which the
bulb and complete papilla have been excised regenerated new papillae
and grew new pigmented hairs.
CONCLUSION. The middle portion of the outer root
sheath and dermal sheath may also contain epithelial, mesenchymal,
and melanocyte reservoirs.
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