Jahoda, 1996 Title: Dermal-epidermal interactions. Adult
follicle-derived cell populations and hair growth.
Authors: Jahoda CA, Reynolds AJ
Journal: Dermatol Clin 1996 Oct;14(4):573-83
PMID: 9238317, UI: 97380960
Affiliated institution: Department
of Biological Sciences, University of Durham, United Kingdom.
Cited in: McCoy
Intrinsic dermal-epidermal interactions are central
to the development and growth of hair. This article describes
investigations into the inductive properties of specific dermal
and epidermal cell populations from adult follicles by means of
cell culture and in vivo implantation. It highlights the inductive
powers of cultured dermal papilla cells and the more recent finding
that the germinative epidermal cells of the lower follicle also
can stimulate hair growth. How the reconstruction of a hair follicle
from its constituent parts has been achieved is described. The
significance of these findings is considered with reference to
human hair growth, tissue engineering, and the prospects for elucidating
the molecular signalling mechanisms that underpin dermal-epidermal
interplay.
|