Cavanagh, 1978 Title: Some effects of a thallium salt on the
proliferation of hair follicle cells.
Authors: Cavanagh JB, Gregson M
Journal: J Pathol 1978 Aug;125(4):179-91
PMID: 722399, UI: 79069371
Affiliated institution:
Cited in: Lin
Thallium sulphate has been given to young rats at
4 and 7 days of age and the mitotic activity of the hair follicles
has been assessed quantitatively. It has been found that there
is a marked decline in mitotic rate over 48 hr in the thallium-treated
animals, which is followed by variable amounts of cell death in
the matrix zone. No specific mitotic lesion was found or change
in cell cycle indices. A failure of energy metabolism is suggested
as a possible cause of the inhibition of hair follicle mitosis
by thallium.
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