Ono, 2000 Title: Histopathological changes in the hair
follicle after irradiation of long-pulse alexandrite laser equipped
with a cooling device.
Authors: Ono I, Tateshita T
Journal: Eur J Dermatol 2000 Jul-Aug;10(5):373-8
PMID: 10882946
Affiliated institution: Division of Plastic
and Reconstructive Surgery, Department of Dermatology, Fukushima
Medical University School of Medicine, Hikarigaoka-1, Fukushima,
Fukushima 960-1295, Japan.
Cited in:
Several laser systems are currently used for epilation. However,
the optimal parameters and treatment protocols remain largely
unknown. In this study, the histopathological changes in the hair
follicles after long pulsed alexandrite laser irradiation are
discussed and the clinical application of irradiation energy at
the time of treatment is described. The laser used in this study
is equipped with a computer controlled cooling device. A histopathological
study was performed to compare the differences in the degree of
degeneration in the epidermis and follicles treated with and without
the cooling device. In comparison with normal hair papilla, in
the laser irradiated skin, injury of melanin containing cells
and hair shafts and external root-sheaths in the periphery were
observed, while the epidermis was completely protected by the
cooling device. The condition of the hair papilla of the tissue
irradiated at a fluence of 25 J/cm2 with a spot diameter of 15
mm and 20 J/cm2, with a spot diameter of 18 mm were investigated
thoroughly. Swollen papilla and selective destruction of the site
where melanocytes were present were observed. The results of this
study strongly indicate the efficacy of a long-pulsed alexandrite
laser equipped with a computer controlled cooling device for clinical
depilation.
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